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新聞新知~維他命健康食品不一定好?

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The toxic truth about vitamin supplements: How health pills millions take with barely a second thought can do more harm than good

維他命健康食品不一定好?

By Lynne Wallis

Last updated at 1:26 AM on 24th August 2010

中文大意

四年前,我因滑雪意外而傷到膝蓋,此後開始服用被大力推廣的glucosamine (葡萄糖胺) 補給丸。glucosamine從貝類動物提煉出來,被大家相信對關節有益,原因是:因為它可加速成長所需的蛋白質生成,並且可維持軟骨的健康。
儘管目前仍未有臨床證據證實它的效果,但我的家庭醫師說它可重建軟骨的傷害,並增強關節的力量。我一點也不懷疑,立即依照指示服用,一天1500mg。
不久之後,我發現跑廁所的次數太過頻繁,有時一天超過5次,腹部不舒服,脹氣、容易放屁,且大便色黑且油,我自我診斷為IBS(急躁性腸症候群)。
我的家庭醫師開了一些放鬆腸子肌肉的藥給我,但沒有用。去年年初,我吃完了glucosamine而沒再繼續補充。我的膝蓋變好了,之後我服用魚油,因為它被宣揚為關節的新的神秘補給配方。過了一些日子,我的腸子恢復正常。可以在今年三月又經歷另一次滑雪意外,傷到同樣的膝蓋,我又開始服用glucosamine。
一個星期後,我的IBS又來了,因此我做了兩者相關的聯想。我研究glucosamine,發現副作用為腹瀉和糞便鬆軟,我再次停止服用,嘿一轉眼的,又恢復了正常...
最近幾年健康食品的販售越來越多,約有4成的英國民眾服用他們。市場龐大,製造商一年花了4000萬英鎊來宣傳他們的產品。
姑且不論營養食品來自天然成分還是假的成份,許多人假設(包括我在內),營養食品無害。
但我們錯了,專家指出,健康食品企業未有明確規範,許多製造商沒有被要求列出成分的潛在副作用,而他們的產品也未經過足夠的臨床實驗。
有一些少數的例外,像是folic acid(葉酸),它被建議給想懷孕的女性,假如你服用400mcg來幫助懷孕,這算是食物。但倘若增加服用量至5mg來治療貧血或其它症狀,它將變成一種藥物,需要執照才能開藥。其他方面,由於缺少檢查和平衡的機制來保護消費者,令人擔憂。
英國飲食學會Anna Raymond說,健康食品是會產生不良後果的。
人們隨意服用健康食品,若是也服用一些藥物或是過量服用,將有害。
的確,glucosamine曾經造成一個男人的死亡。在2004年,Norman Ferrie,一位丹地(蘇格蘭東部港市)的64歲的工程師,因服用該種營養品數週後,肝功能衰竭而死亡。丹地Ninewells醫院的腸胃學家Dr John Dillon對調查死因的陪審團表示:他的肝原本是正常的,有某種東西發作所造成。另外還有兩個案例,是廣泛使用健康食品而導致激烈的反應。
Dillon說:越來越多人,期望服用神奇的藥物使他們更健康。許多人不知道glucosamine和其他健康食品只被許可為食物,但卻被以藥物販賣。
要求健康食品製造者列出嚴重的危險是合理的。
我們所需的營養皆可從健康的飲食取得。大量的健康食品是浪費錢的。人們感覺毛毛的,並開始服用他們不需要的健康食品。可能得到hypervitaminosis(維他命過多症),而致命。會導致嘔吐、昏睡、腎功能衰竭。人們可以服用的時機為:當醫師建議服用時。
但在醫師的建議下服用也並非沒有危險,上個月,有報導指出,服用鈣補給品(經常被建議給骨質疏鬆者),將提高心臟病發30%的機率。
Health Supplement Information Service的營養學家Dr Carrie Buxton說:並非只有主要成分才會產生問題,另一個危險是:服用者可能對藥物中的某些成分過敏,像是binding agent(結合劑)和gel coating(凝膠劑)。
話雖如此,Food Standards Agency(食品標準局)表示,關於健康食品的法規已經足夠,不用再加。那你該如何確保自己的安全?
營養學家Anna Raymond建議:每個人開始服用健康食品,就必須告訴他的家庭醫師,此外,我們發現一些健康食品的負面影響,是你不會在包裝上看到的。
(以下內容僅節錄,詳細請參考原文)
 
GLUCOSAMINE葡萄糖胺
這是啥:
從螃蟹和龍蝦殼中提煉出來(若你對海鮮過敏也不能吃),通常用來緩和關節炎的症狀。
副作用:
根據Arthritis Research Campaign(關節研究活動),包含胃部不適、便秘、腹瀉、頭痛、起疹子。也將與「糖尿病治療」的「增加血糖濃度治療」產生反應。
 
KELP海草
這是啥:
從海草中提煉出來,而海草是世界上生長最快的水藻,一天可長兩英呎,大量分佈於北加州海岸。KELP豐有某些礦物質。例如富有碘,人體缺乏碘將導致甲狀腺問題。它被歸類為治療甲狀腺不均衡,不均衡的原因為由於甲狀腺素製造太多或太少。
副作用:
它是個血液稀釋劑,不能與阿斯匹林和任何降血壓藥共用。
 
POTASSIUM 鉀
這是啥:
鉀的平衡可維持骨骼健康和身體機能。
副作用:
過量服用將導致心律不整…等等
 
MELATONIN退黑激素
由腦袋中的松果腺生成的腺素,幫助睡眠。
營養品可以幫助調整睡眠。
副作用:
增加血壓、頭痛、降低體溫、憂鬱。
 
CALCIUM鈣
這是啥:
成長時骨骼牙齒的必要礦物質。
副作用:
女性服用將增加30%的心臟病危險。

英文原文

Four years ago, I began taking the much promoted glucosamine supplement after hurting my knee in a skiing accident. 

Glucosamine is made from shellfish and is widely believed to promote joint health - the theory is that it speeds up the production of the protein needed to grow and maintain healthy cartilage. 

Although there's no clinical evidence of its effectiveness, my GP said it might help rebuild the damaged cartilage and improve my joint strength. I didn't hesitate, and immediately started taking the recommended dose, 1,500 mg a day.

Toxic tablet: Headaches, diarrhoea and a flagging libido can be side effects of taking some vitamin supplements

Not long after, I found I needed to go to the lavatory far too often - sometimes more than five times a day. I had abdominal discomfort, bloating, gas and my stools were dark and tarry. I self- diagnosed IBS.

My GP prescribed drugs to relax the bowel muscles, but they didn't help. Then, early last year, I ran out of glucosamine and didn't restock. My knee was better and I was taking fish oils, which were being promoted as the new miracle supplement for joints.

Within a few days, my bowels returned to normal and remained so until, after another ski accident damaging the same knee in March this year, I began taking glucosamine again.

Within a week my 'IBS' had returned and I made the link. I researched glucosamine and found that side-effects include diarrhoea and loose stools. I stopped again and, hey presto, everything's back to normal.

Sales of health supplements have soared in recent years, with 40 per cent of Britons taking them. It's such a huge market that manufacturers spend around £40 million a year just telling us about their products. 

 

As supplements are either made from natural substances or mimic substances produced by our bodies, many people, like me, assume they cannot do any harm.

But we're wrong, say health professionals. They point out that the health supplement industry is unregulated, which means manufacturers are not required to list potential side-effects - nor do their products have to go through costly clinical trials.

There are a handful of exceptions, such as folic acid, which is recommended for women trying to conceive. If you take a tablet of 400 micrograms (mcg) strength to help with conception, it is classed as a food.

But increase the dose to 5 mg (to treat anaemia and other conditions) and it becomes a medicine, requiring a licence. Otherwise, there are no checks and balances to protect consumers. And this worries experts.

'Health supplements can produce ill effects,' warns Anna Raymond, from the British Dietetic Association.

'People take supplements randomly, but they can be toxic if taken with some medicines or in high quantities.' 

Indeed, glucosamine has been linked to the death of one man. In 2004, Norman Ferrie, a 64-year-old engineer from Dundee, died of liver failure within weeks of taking the supplement.

'The liver had been normal and something had attacked it,' gastroenterologist Dr John Dillon, of Ninewells Hospital, Dundee, told the inquest in 2008. He said there had been two other cases involving extreme reactions to the widely used supplement.

'Increasingly, people are being taken in by the prospect of a magic pill that will make them healthy,' says Dr Dillon. 'Most people don't know that glucosamine and other supplements are only licensed as a food, but are sold as a medicine.

'It would seem fair to ask manufacturers of supplements to list serious risks.

'Everything we need can be got from a healthy diet. The vast majority of health supplements are a waste of money. People feel fluey and start taking supplements they don't need. They could end up with hypervitaminosis, caused by excessive amounts of supplements.'

This can lead to vomiting, lethargy and even renal failure. 'The only time a person should take a supplement is if a doctor recommends it,' adds Dr Dillon.

Needless habit: Experts say it's better to have a healthy diet than take supplements

But even taking supplements on doctors' recommendations is not risk free. Last month, it was reported that taking calcium supplements - often prescribed for osteoporosis - could raise the risk of heart attacks by 30 per cent. 

And it's not just the main ingredient than causes problems. Another risk is having an allergy to one of the constituents of a tablet, such as a binding agent or the gel coating, says nutritionist Dr Carrie Buxton, from the Health Supplement Information Service. 
Despite the concerns, the Food Standards Agency says legislation on supplements is adequate. So, what can you do to ensure your safety? 

Dietitian Anna Raymond advises anyone who starts taking supplements should tell their GP. And here we identify some of the supplements with potentially negative effects you won't find listed on the packet. 
 

GLUCOSAMINE

WHAT IT IS: The supplement, which is made from crab and lobster shells (so should be avoided if you have a seafood allergy), is often taken to ease the symptoms of arthritis. 

POTENTIAL SIDE-EFFECTS: According to the Arthritis Research Campaign, these can include stomach upset, constipation, diarrhoea, headache and rash; glucosamine can also react with anti-diabetic treatments by increasing blood sugar levels. 

The UK Commission on Human Medicines has noted that glucosamine has a negative interaction with the blood-thinning drug warfarin and warns against taking these substances simultaneously. 

The supplement might also cause water retention, as it attracts water. 

KELP

WHAT IT IS: This supplement is made from a seaweed which is the fastest-growing marine algae in the world - it can grow two feet in one day and is most abundant off the north California coast. 

Kelp is a rich source of several minerals and trace elements, including iodine - deficiency of which can lead to an underactive thyroid. It is marketed as a treatment for thyroid imbalance, caused by the thyroid gland producing either too much or too little of the hormone. 

POTENTIAL SIDE-EFFECTS: Despite the claims made for it, studies have linked kelp to an increased risk of thyroid dysfunction. It's also a blood thinner and shouldn't be taken with aspirin or any medicine to lower blood pressure. 

There's also concern that some kelp is being harvested from kelp 'forests' in polluted oceans, which means it could be toxic. In 2007, research at the University of California found high levels of arsenic in eight out of nine kelp supplements. Arsenic is linked to hair loss, headaches, confusion and drowsiness. 

POTASSIUM

WHAT IT IS: Maintaining an adequate potassium level is important for bone health and the proper functioning of the body. Potassium supplements are often taken to help combat insulin resistance, arthritis and menopausal symptoms such as fatigue and mood swings. 

POTENTIAL SIDE-EFFECTS: Taken in very high doses as a supplement, potassium can have serious side-effects such as arrhythmia (faulty heartbeat) - and it can even be fatal. 

Research at Oregon State University has also linked it to muscle weakness, confusion, stomach pain and numbness or tingling in the hands, feet or mouth. 

Potassium supplements react badly with some medicines, and shouldn't be taken by anyone suffering from kidney or heart disease, severe dehydration or high blood pressure. 

Older people who often have too much potassium in their bodies should avoid these supplements - kidneys are less efficient at eliminating potassium as we age. 

MELATONIN

WHAT IT IS: Natural melatonin is a hormone made by the pineal gland in the brain and helps to regulate sleep. 

Supplements can control our sleep/ wake cycles and are used to treat sleep disorders. British manufacturers make medical claims about its sleep benefits, so here it is licensed as a prescription- only medicine - however it is freely available in the 

U.S. POTENTIAL SIDE-EFFECTS: These include raised blood pressure, vivid dreams, headache, lower body temperature, fatigue, depression, decreased libido and reduced fertility. 

A daily dose of 1- 3 mg of melatonin increases the body's levels of melatonin by 20 times the normal amount. The British Pharmaceutical Society says that studies on its effectiveness to treat jet-lag have been conflicting. 

CALCIUM

WHAT IT IS: Calcium is an essential mineral for the growth and maintenance of healthy bones and teeth and for blood clotting, muscle contraction, healthy nerves and good hormone function. It is usually taken by women to boost bone health. 

POTENTIAL SIDE-EFFECTS: Research published last month by Auckland and Aberdeen universities reflected other studies in finding a 30 per cent increased risk of heart attack among women taking calcium supplements - most women taking them are postmenopausal and concerned about osteoporosis. 

This increase is due to the risk of calcium supplements accelerating the hardening of blood vessels. Doctors involved with a 2008 New Zealand study advise women of 70 or older not to take calcium supplements.

資料來源: 
 
Mail online News
 
The toxic truth about vitamin supplements: How health pills millions take with barely a second thought can do more harm than good

 

 

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